MCM3 (minichromosome maintenance complex component 3)
نویسندگان
چکیده
منابع مشابه
MCM 5 ( minichromosome maintenance complex component 5 )
The unique transcript of the MCM5 gene is 2546 nt. The human MCM5 gene was shown to be expressed widely in many normal tissues, but its mRNA levels vary a lot. The highest levels of MCM5 mRNA transcripts were detected in A-431 epidermoid carcinoma cells, U-2 OS osteosarcoma cells, and U-251 MG astrocytoma cells. Expression of all human genes of the MCM family is induced by growth stimulation an...
متن کاملEvaluation of Minichromosome Maintenance-3 (MCM3) in Oral Squamous Cell Carcinoma
STATEMENT OF THE PROBLEM The expression of minichromosome maintenance-3 (MCM3) proteins and their diagnostic value in oral mucosal dysplasia and squamous cell carcinoma (SCC) is not well known. PURPOSE This study was conducted to evaluate the usefulness of minichromosome maintenance 3 (MCM3) as a biomarker for diagnosis of oral premalignant lesions and SCC. MATERIALS AND METHOD In this stud...
متن کاملUpregulation of minichromosome maintenance complex component 3 during epithelial-to-mesenchymal transition in human prostate cancer
Metastasis is often associated with epithelial-to-mesenchymal transition (EMT). To understand the molecular mechanisms of this process, we conducted proteomic analysis of androgen-repressed cancer of the prostate (ARCaP), an experimental model of metastatic human prostate cancer. The protein signatures of epithelial (ARCaPE) and mesenchymal (ARCaPM) cells were consistent with their phenotypes. ...
متن کاملevaluation of minichromosome maintenance-3 (mcm3) in oral squamous cell carcinoma
statement of the problem: the expression of minichromosome maintenance-3 (mcm3) proteins and their diagnostic value in oral mucosal dysplasia and squamous cell carcinoma (scc) is not well known. purpose: this study was conducted to evaluate the usefulness of minichromosome maintenance 3 (mcm3) as a biomarker for diagnosis of oral premalignant lesions and scc. materials and method: in this study...
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We investigated the role of lamin B2 in non-small cell lung cancer (NSCLC). We detected higher lamin B2 expression in 20 NSCLC tumor tissues obtained from The Cancer Genome Atlas than in adjacent normal lung tissues. LMNB2-RNAi knockdown in A549 and H1299 NSCLC cells inhibited colony formation, cell proliferation and G1-S cell cycle progression while increasing apoptosis. LMNB2 overexpression h...
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2017
ISSN: 1768-3262
DOI: 10.4267/2042/62479